When Manchester United take on Brighton on Saturday evening at the Amex Stadium, Alejandro Garnacho might make his full debut for the club (5.30pm). A number of players, notably England duo Jadon Sancho and Marcus Rashford, will miss the match for the second time in succession.

Sancho and Rashford are both out with illness, while injuries to Luke Shaw (leg), Eric Bailly (back), and Paul Pogba (calf) continue to be the most serious concerns for the team. Some hopeful news has emerged as Aaron Wan-Bissaka (knock) and £80 million captain Harry Maguire both return to the starting lineup.

There have been mounting requests for Garnacho to be given a genuine shot at the end of the season after he made his debut with a two-minute cameo against Chelsea on September 1. The question is whether or not that opportunity will present itself at the Amex Stadium against a Brighton side in good form and fighting for a top-half finish.

David de Gea is the team's goalkeeper.

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In the Premier League so far this season, David de Gea has appeared in all 36 games. This will not be the first time he has been the greatest and most consistent player.
Injuries have hampered Manchester United's backline, which has been severely affected. It is possible, though, that some good news will come out of this situation as Wan-Bissaka and Maguire prepare to return to the competition. Fans have called for continuity following Brentford's victory, and neither player has been selected for this match.

It was a tear-jerking send-off for Nemanja Matic and Juan Mata on Monday night at Old Trafford. In addition to the Amex Stadium, Rangnick has been encouraged to recall Fred by the club's supporters, and Scott McTominay is given another opportunity to turn his season around before the season ends.

Having single-handedly carried the fight in attacking areas this season with 24 goals - 18 of which have come in the Premier League alone - Cristiano Ronaldo will take the field. Because of injuries and illness, he is running out of options for partners, and it is possible that academy graduates Anthony Elanga and Garnacho will be flanking him on Saturday afternoon.