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hMSH2 is a critical element of the highly conserved DNA mismatch repair system, normally located in the nucleus and dimerized with human MutS homologue 3 (hMSH3) or human MutS homologue 6 (hMSH6) to form complexes essential for the maintenance of genome integrity. Inherited and acquired defects in hMSH2 are closely related to the pathogenesis of hereditary nonpolyposis colon cancer as well as various sporadic cancers. hMSH2 and γδ T Cells https://gammadelta-t-therapy.c....reative-biolabs.com/

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Human MutS Homologue 2 (hMSH2) - Creative Biolabs

hMSH2 plays important roles in DNA damage signaling, apoptosis, and antibody class switch recombination in B cells.