Barcelona will take on Manchester United in what is arguably the tie of the round.
Juventus have been drawn against Nantes and Ajax will face Union Berlin.
The first legs of the last playoff round will be played on February 16, 2023, before the return legs a week later.
FULL FIXTURES
Barcelona vs Manchester United
Juventus vs Nantes
Sporting Lisbon vs FC Midtjylland
Shakhtar Donetsk vs Rennes
Ajax vs Union Berlin
Bayer Leverkusen vs Monaco
Sevilla vs PSV
Salzburg vs Roma
Alphonsus Odumu 2 d
Europa League